Figure 2.

The causality of systemic lupus erythematosus on breast cancer risk in East Asians. (A) Forest plot. The red points demonstrate the integrated estimates using all SNPs together, using IVW method. Horizontal lines represent 95% confidence intervals. (B) Leave-one-out analysis. Black points depict the IVW method was used to assess the causal effect, excluding single specific variant from the analysis. The red point denotes the inverse-variance weighted estimate using all SNPs. (C) Scatter plot. The slope of each line denotes the estimated effect of per mendelian randomization method. (D) Funnel plot. Vertical lines represent estimates with all SNPs. Symmetry in the funnel plot demonstrates no obvious horizontal pleiotropy. IVW, Inverse‐variance weighted; SNP, single-nucleotide polymorphism.