Table 3.

Correlations of gene markers.

Type	Gene marker	SLEscore
		Cor	P-value
ICB
	PD-L1	0.14	9.1e-0.7*
	Lag3	0.19	1.2e-11*
	CTLA-4	0.2	1e-12*
	CD47	0.3	0*
	TIM	0.17	7.5e-09*
	TIGIT	0.18	1e-09*
	HAVCR2	0.17	7.5e-09*
	DNAM-1	0.15	2.8e-0.7*
Apoptosis
	TNF	0.22	3.2e-14*
	Bcl-2	-0.076	0.0082*
	SMAC	0.38	0*
	NLRP3	-0.26	1.4e-19*
	XIAP	0.15	1.9e-07*
Pyroptosis
	SEMA3B	-0.1	0.00053*
	IGKC	0.013	0.64
	KLRB1	-0.14	5.9e-07*
	BIRC3	0.082	0.0046*
	PSME2	0.29	0*
	GZMA	0.068	0.018*
	GZMB	0.19	2.4e-11*
	IL18	0.11	8.5e-05*
	IRF1	0.16	1.4e-08*
Necroptosis
	FASLG	0.15	1.2e-07*
	IPMK	0.24	0*
	FLT3	0.06	0.0036*
	SLC39A7	0.24	0*
	HSP90AA1	0.43	0*
	LEF1	0.08	0.0079*

*, statistically significant; Cor, the value of Pearson’s correlation; ICB, immune checkpoint blockade.

The bold values means statistical significance.