Table 2.
Outcomes of receiver operating characteristic curves and Youden index for six candidate miRNAs and the panels.
| AUC | p-value | 95% CI | Associated criterion |
Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|---|
| miR-1-3p | 0.647 | 0.0010 | 0.569–0.720 | ≤1.15 | 87.80 | 45.12 |
| miR-124-3p | 0.633 | 0.0026 | 0.554–0.706 | ≤1.04 | 82.93 | 45.12 |
| miR-129-5p | 0.743 | <0.001 | 0.669–0.808 | ≤0.92 | 71.95 | 70.73 |
| miR-155-5p | 0.647 | 0.0009 | 0.568–0.720 | >1.03 | 64.63 | 67.09 |
| miR-200b-3p | 0.747 | <0.001 | 0.674–0.812 | ≤0.98 | 87.80 | 52.44 |
| miR-224-5p | 0.730 | <0.001 | 0.655–0.796 | >1.1 | 69.51 | 70.73 |
| four-miRNA panel | 0.903 | <0.001 | 0.847–0.944 | >0.62787 | 75.61 | 93.67 |
AUC, area under curve; CI, confidence interval.