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. 2023 Jan 16;13:1079415. doi: 10.3389/fimmu.2022.1079415

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Copyright © 2023 Li, Liao, Du, Hu, Wang, Song, He, Xiao and Ye

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of mRNA levels of TSLP isoforms between RA patients and HC. (A) RT-qPCR analysis of the mRNA expression of sTSLP and lTSLP in PBMCs from RA patients (n = 68) versus HC (n = 66). (B) RT-qPCR comparison of sTSLP and lTSLP mRNA expression in PBMCs from HC and RA patients. (C, D) RT-qPCR analysis of sTSLP and lTSLP mRNA levels in active and inactive RA patients was compared to HC. (E) RT-qPCR analysis of the mRNA expression of lTSLP in RA patients with or without prednisolone treatment. (F) RT-qPCR analysis of lTSLP mRNA expression in HC and in active and inactive RA patients following prednisolone treatment. Data are depicted as a violin plot. (A-F) were analyzed by unpaired two-tailed Student’s t-test. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. ns, no significant.