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. 2023 Jan 16;13:1101429. doi: 10.3389/fimmu.2022.1101429

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Copyright © 2023 Jalandra, Makharia, Sharma and Kumar

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of TMA on cell cycle progression. Evaluation of cell cycle HCT116 (A) and HT29 (B) cells were treated with various concentrations of TMA for 48 h. Untreated cells were considered as negative control. (A) and (B) showed the quantification of cell cycle distribution. TMA induced cell cycle arrest. 1, 2, 3, and 4 represent control, 1.25 mM, 5 mM and 10 mM treatment respectively. The distribution of various phase of HCT116 and HT29 cells are represented in (C, D) Difference of average values between untreated and treated cells were tested using one-way ANOVA. The results (mean±SEM) were obtained from 3 independent experiments. *indicates significantly different values compared to control group (P<0.05).