Table 2.

Eradication rate of each treatment group.

Analysis	L-VA	H-VA	Difference from H-VA (adjusted 95% CI for difference)	P value for difference*	P value for non-inferiority †
ITT	89.1% (49/55)	87.3% (48/55)	1.8% (-12.1% to 15.7%)	0.768	0.616
95% CI	77.1% to 95.5%	74.9% to 94.3%
PP	94.1% (48/51)	95.9% (47/49)	1.8% (-10.1% to 13.6%)	0.68	0.339
95% CI	82.8% to 98.5%	84.9% to 99.3%

*P-values were obtained from two-sided comparisons of the difference between the L-VA group and the H-VA group; †The P values were obtained from one-sided test comparisons of non-inferiority between the L-VA group and the H-VA group. ITT, intention to treat; PP, per protocol; L-VA, dual therapy consisting of low-dose amoxicillin (1000 mg b.i.d.) and vonoprazan (20 mg b.i.d.); H-VA, dual therapy consisting of high-dose amoxicillin (1000 mg t.i.d.) and vonoprazan (20 mg b.i.d.).