Table 4.
Factors influencing cure rates in the per-protocol population.
| Variables | L-VA | H-VA |
|---|---|---|
| Gender | ||
| Male | 19/21 (90.5%) | 23/25 (92.0%) |
| Female | 29/30 (96.7%) | 24/24 (100.0%) |
| P value | 0.355 | 0.157 |
| Age | ||
| <45 | 25/26 (96.2%) | 30/31 (96.8%) |
| ≥45 | 23/25 (92.0%) | 17/18 (94.4%) |
| P value | 0.529 | 0.691 |
| BMI | ||
| <24 | 30/32 (93.8%) | 33/35 (94.3%) |
| ≥24 | 18/19 (94.7%) | 14/14 (100.0%) |
| P value | 0.885 | 0.361 |
| Education status | ||
| High school or less | 22/23 (95.7%) | 23/24 (95.8%) |
| College or more | 26/28 (92.9%) | 24/25 (96.0%) |
| P value | 0.673 | 0.976 |
| Cigarette smoking | ||
| Yes | 7/7 (100.0%) | 9/10 (90.0%) |
| No | 41/44 (93.2%) | 38/39 (97.4%) |
| P value | 0.476 | 0.289 |
| Alcohol drinking | ||
| Yes | 17/18 (94.4%) | 17/17 (100.0%) |
| No | 31/33 (93.9%) | 30/32 (93.8%) |
| P value | 0.942 | 0.293 |
| Family-based H. pylori infection | ||
| Yes | 19/20 (95%) | 11/11 (100.0%) |
| No | 29/31 (93.5%) | 36/38 (94.7%) |
| P value | 0.83 | 0.437 |
| Indications | ||
| Peptic ulcers | 6/6 (100.0%) | 4/4 (100.0%) |
| Dyspepsia | 2/2 (100.0%) | 4/5 (80.0%) |
| Gastritis | 15/18 (83.3%) | 14/14 (100.0%) |
| H. pylori confirmed | 25/25 (100.0%) | 25/26 (96.2%) |
| P value | 0.119 | 0.261 |
BMI, body mass index; L-VA, dual therapy consisting of low-dose amoxicillin (1000 mg b.i.d.) and vonoprazan (20 mg b.i.d.); H-VA, dual therapy consisting of high-dose amoxicillin (1000 mg t.i.d.) and vonoprazan (20 mg b.i.d.).