Table III.

Association between pruritus and psychological symptoms in adjusted multivariate logistic regression analyses

Pruritus	Never	Seldom Adjusted OR (95% CI)	Monthly Adjusted OR (95% CI)	Weekly Adjusted OR (95% CI)	Daily Adjusted OR (95% CI)
Generalized Anxiety Disorder Screener-7	Ref
Pruritus in limited areas
7–10		1.32 (0.92–1.88)	1.82 (1.22–2.73)	2.01 (1.32–3.07)	1.50 (0.88–2.56
>10		1.55 (0.91–2.66)	2.13 (1.18–3.87)	2.46 (1.34–4.51)	3.69 (1.95–7.01)
Generalized pruritus
7–10		1.36 (1.04–1.78)	1.47 (0.93–2.31)	1.95 (1.19–3.18)	2.46 (1.35–4.48)
>10		1.18 (0.81–1.71)	2.62 (1.60–4.28)	2.04 (1.07–3.87)	3.30 (1.65–6.59)
Beck Depression Inventory-II	Ref
Pruritus in limited areas
14–20		0.82 (0.58–1.17)	1.67 (1.14–2.44)	1.58 (1.05–2.38)	1.68 (1.05–2.70)
>20		1.68 (1.00–2.81)	1.81 (1.00–3.26)	3.61 (2.07–6.28)	2.88 (1.51–5.52)
Generalized pruritus
14–20		1.30 (0.99–1.71)	2.66 (1.81–3.91)	1.72 (1.04–2.86)	1.43 (0.72–2.86)
>20		2.02 (1.41–2.88)	2.64 (1.57–4.44)	2.67 (1.45–4.94)	4.27 (2.22–8.19)
Hopkins Symptom Checklist-25	Ref
Pruritus in limited areas
1.55–1.75		1.48 (1.10–1.99)	1.87 (1.33–2.62)	1.94 (1.35–2.78)	2.33 (1.54–3.51)
>1.75		1.77 (1.29–2.41)	2.45 (1.73–3.47)	3.52 (2.48–5.00)	3.89 (2.62–5.78)
Generalized pruritus
1.55–1.75		1.45 (1.18–1.80)	1.31 (0.88–1.93)	1.44 (0.92–2.24)	1.28 (0.70–2.33)
>1.75		1.82 (1.47–2.26)	2.91 (2.10–4.04)	3.65 (2.55–5.24)	3.94 (2.52–6.16)

Multivariate logistic regression analyses, adjusted with the following confounder factors: smoking, alcohol use, body mass index (BMI), physical activity, socioeconomic status, and the history of skin disease.

OR: odds ratio; 95% CI: 95% confidence interval.