Table 3.
Genes/gene clusters of heavy metal resistance in R. planticola FACU 3
| Genes | Function | length | Heavy metal resistance | Locus tag |
|---|---|---|---|---|
| zntAb | Zinc/cadmium/lead-transporting P-type ATPase | 2199 | Zn, Cd, Pb | NM584_04589 |
| chrRc | Quinone reductase | 567 | Cr | NM584_03451 |
| arsA | Arsenical pump-driving ATPase | 1752 | As | NM584_05684 |
| arsBc | Arsenical pump membrane proteina |
1293 1290 1167 |
As |
NM584_01807 NM584_05685 NM584_05812 |
| arsCc | Arsenate reductasea |
426 426 429 |
As |
NM584_01808 NM584_05686 NM584_05813 |
| arsHc | NADPH-dependent FMN reductasea |
699 723 |
As |
NM584_01805 NM584_05814 |
| arsDc | Arsenical resistance operon trans-acting repressor | 363 | As | NM584_05683 |
| arsRc | Arsenic resistance transcriptional regulator | 354 | As | NM584_05653 |
| rcnRb | Transcriptional repressor RcnR | 272 | Ni, Co | NM584_00068 |
| rcnBb | Nickel/cobalt homeostasis protein RcnB | 318 | Ni, Co | NM584_02529 |
| hoxNb | High-affinity nickel transport protein | 1014 | Ni | NM584_01839 |
| cnrAb | Nickel and cobalt resistance protein | 3183 | Ni, Co | NM584_00460 |
| nikAc | Nickel-binding periplasmic proteina |
1569 1623 |
Ni |
NM584_03175 NM584_04730 |
| nikBc | Nickel transport system permease protein | 945 | Ni | NM584_03176 |
| nikCc | Nickel transport system permease protein | 834 | Ni | NM584_03177 |
| nikDc | Nickel import ATP-binding protein | 765 | Ni | NM584_03178 |
| nikEc | Nickel import ATP-binding protein | 792 | Ni | NM584_03179 |
| nikRc | Nickel-responsive regulator | 417 | Ni | NM584_03180 |
| zitBb | Zinc transporter ZitB | 939 | Zn | NM584_00719 |
| zntBb | Zinc transport protein ZntBa |
1029 934 |
Zn |
NM584_02816 NM584_04340 |
| zntRb | HTH-type transcriptional regulator | 426 | Zn | NM584_05551 |
| znuAb | High-affinity zinc uptake system protein ZnuA | 945 | Zn | NM584_01443 |
| znuCb | Zinc import ATP-binding protein ZnuC | 753 | Zn | NM584_01442 |
| znuBb | High-affinity zinc uptake system membrane protein ZnuB | 786 | Zn | NM584_01441 |
| yeiRb | Zinc-binding GTPase YeiR | 978 | Zn | NM584_02585 |
| zurb | Zinc uptake regulation protein | 516 | Zn | NM584_05063 |
| ftsHb | ATP-dependent zinc metalloprotease FtsH | 1944 | Zn | NM584_04403 |
| zupTb | Zinc transporter ZupT | 771 | Zn | NM584_02221 |
| copAb |
Copper-exporting P-type ATPase Copper resistance protein A |
2502 1818 |
Cu Cu |
NM584_01046 NM584_05521 |
| copBb | Copper resistance protein B | 897 | Cu | NM584_05520 |
| pcoC | Copper resistance protein C | 381 | Cu | NM584_05519 |
| copDb | Copper resistance protein D | 930 | Cu | NM584_05518 |
| copRb | Transcriptional activator proteina |
681 702 |
Cu |
NM584_05517 NM584_01018 |
| sasAb | Adaptive-response sensory-kinase | 1401 | Cu | NM584_05516 |
| pcoEb | putative copper-binding protein PcoE | 435 | Cu | NM584_05515 |
| cutCb | Copper homeostasis protein CutC | 744 | Cu | NM584_01429 |
| cueOb | Blue copper oxidase | 1626 | Cu | NM584_03744 |
| cueRb | HTH-type transcriptional regulator CueR | 411 | Cu | NM584_01041 |
| cusAb | Cation efflux system protein CusAa |
3156 3146 |
Cu, Ag |
NM584_03841 NM584_05527 |
| cusBb | Cation efflux system protein CusBa |
1278 1293 |
Cu, Ag |
NM584_03840 NM584_05528 |
| cusFb | Cation efflux system protein CusFa |
348 354 |
Cu, Ag |
NM584_03839 NM584_05529 |
| cusCb | Cation efflux system protein CusCa |
1482 1494 1386 |
Cu, Ag |
NM584_02048 NM584_03838 NM584_05530 |
| cusRb | Cation efflux system protein CusRa |
684 681 |
Cu, Ag |
NM584_03837 NM584_05531 |
| cusSb | Sensor histidine kinase CusSa |
1452 1467 |
Cu, Ag |
NM584_03836 NM584_05532 |
| silEb | Silver-binding proteina |
450 432 |
Ag |
NM584_05522 NM584_05533 |
| silPb | Silver exporting P-type ATPase | 2442 | Ag | NM584_05525 |
| merRb | Transcriptional regulatora |
399 456 |
Hg |
NM584_00139 NM584_02915 |
Numbers depict relevant contigs, Locus tags are from Prokka annotation
aSome genes exist in multiple copies and locations, bGenes located on chromosome, cGenes located on plasmid