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. 2023 Jan 30;13:14. doi: 10.1186/s13568-023-01519-w

Table 4.

The AMR genes annotated in this genome and corresponding AMR mechanism

Genes ABR mechanism
katG Antibiotic activation enzyme
PLA family Antibiotic inactivation enzyme
marA, marB, marR Antibiotic resistance gene cluster or operon
alr, ddl, dxr, EF-G, EF-Tu, folA, Dfr, folP, gyrA, gyrB, inhA, fabI, Iso-tRNA, kasA, MurA, rho, rpoB, rpoC, S10p, S12p Antibiotic target in susceptible species
bcrC Antibiotic target protection protein
acrAB-TolC, acrAD-TolC, acrZ, emrAB-TolC, emrD, macA, macB, mdfA/Cmr, mdtABC-TolC, mdtL, sugE, tolC/OpmH Efflux pump conferring antibiotic resistance
gdpD, pgsA Protein altering cell wall charge conferring antibiotic resistance
oprB Protein modulating permeability to antibiotic
acrAB-TolC, emrAB-TolC, H-NS, oxyR Regulator modulating expression of antibiotic resistance genes