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. 2023 Jan 18;11(2):e218–e228. doi: 10.1016/S2214-109X(22)00506-X

Table 3.

Adults receiving inhaled and oral asthma medicines according to symptom severity stratified by country income group

High-income countries (n=2724)
Upper-middle-income countries (n=2575)
Lower-middle-income and low-income countries (n=1378)
Asymptomatic (n=1412) Mild symptoms (n=677) Severe symptoms (n=635) Asymptomatic (n=1085) Mild symptoms (n=551) Severe symptoms (n=939) Asymptomatic (n=618) Mild symptoms (n=276) Severe symptoms (n=484)
Inhaled medicine*
SABA (n=3030) 314 (22·2%) 391 (57·8%) 471 (74·2%) 262 (24·1%) 366 (66·4%) 727 (77·4%) 112 (18·1%) 109 (39·5%) 278 (57·4%)
LABA (n=718) 39 (2·8%) 53 (7·8%) 80 (12·6%) 47 (4·3%) 128 (23·2%) 230 (24·5%) 49 (7·9%) 23 (8·3%) 69 (14·3%)
Corticosteroids (n=1118) 134 (9·5%) 189 (27·9%) 230 (36·2%) 51 (4·7%) 70 (12·7%) 282 (30·0%) 51 (8·3%) 28 (10·1%) 83 (17·1%)
Corticosteroids and LABA (n=1280) 151 (10·7%) 199 (29·4%) 284 (44·7%) 52 (4·8%) 79 (14·3%) 223 (23·7%) 76 (12·3%) 65 (23·6%) 151 (31·2%)
Any inhaled medicine (n=3646) 350 (24·8%) 439 (64·8%) 534 (84·1%) 333 (30·7%) 409 (74·2%) 823 (87·6%) 178 (28·8%) 185 (67·0%) 395 (81·6%)
Oral medicine*
LTRA (n=520) 71 (5·0%) 46 (6·8%) 80 (12·6%) 47 (4·3%) 46 (8·3%) 192 (20·4%) 10 (1·6%) 4 (1·4%) 24 (5·0%)
Corticosteroids (n=602) 59 (4·2%) 62 (9·2%) 114 (18·0%) 49 (4·5%) 40 (7·3%) 231 (24·6%) 12 (1·9%) 5 (1·8%) 30 (6·2%)
SABA (n=1004) 101 (7·2%) 127 (18·8%) 185 (29·1%) 83 (7·6%) 64 (11·6%) 316 (33·7%) 29 (4·7%) 29 (10·5%) 70 (14·5%)
Theophylline (n=307) 47 (3·3%) 40 (5·9%) 68 (10·7%) 18 (1·7%) 27 (4·9%) 78 (8·3%) 1 (0·2%) 5 (1·8%) 23 (4·8%)
Any oral medicine (n=2226) 177 (12·5%) 227 (33·5%) 320 (50·4%) 159 (14·7%) 195 (35·4%) 613 (65·3%) 133 (21·5%) 125 (45·3%) 277 (57·2%)
Asthma management plan (n=3168) 461 (32·6%) 270 (39·9%) 321 (50·6%) 521 (48·0%) 276 (50·1%) 651 (69·3%) 217 (35·1%) 128 (46·4%) 323 (66·7%)

Data are n (%) where denominators are the total number in each symptom severity category per income group. Percentages with 95% CIs clustered by centre are provided in appendix 2 (p 7). SABA=short-acting β2 agonist. LABA=long-acting β2 agonist. LTRA=leukotriene receptor antagonist.

*

Drug therapy groups are not mutually exclusive and participants could be represented in more than one group.

Combined in the same inhaler; patients using LABA and corticosteroids in separate inhalers were included in the corresponding single-agent treatment groups.