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. 2022 Jul 21;20(2):543–553. doi: 10.1111/iwj.13901

TABLE 1.

Characteristics of included studies

Study Sample size Design Age (years) Male (%) Hemorrhoid grade Sucralfate dose Control group Outcomes a
Ala et al 31 48 Double‐blind RCT 41.5 ± 12.1 50% Grade III and IV Sucralfate 10% Placebo 1,2,3,4,5,6
Albatanony et al 32 90 Double‐blind RCT 37.2 ± 10.7 45.5%

Grade III: 80%

Grade IV: 20%

Sucralfate 10% Placebo 1,2,3,4,5,6,7
Al Khateeb et al 33 50 Prospective RCT 41.2 ± 10.8 46%

Grade III: 54%

Grade IV: 46%

Sucralfate 8% Placebo 1,2,3,7
Alkhateep et al 34 95 Double‐blind RCT 42.4 ± 7.7 50.5%

Grade III: 77.8%

Grade IV: 22.2%

Sucralfate 10% Placebo 1,2,3,7
Gupta et al 35 116 Double‐blind RCT 44.9 ± 11 52.5%

Grade III: 74.1%

Grade IV: 25.9%

Sucralfate 7% Placebo 2,3,7
Vejdan et al 36 40 Single‐blind RCT N/A N/A Grade III and IV Sucralfate 10% Placebo 1
a

Outcomes: 1 = VAS at 24 hours post‐operative; 2 = VAS at 7 days post‐operative; 3 = VAS at 14 days post‐operative; 4 = Pethidine used (mg) within 24 hours post‐operative; 5 = diclofenac used (mg) at 7 days post‐operative; 6 = diclofenac used (mg) at 14 days post‐operative; 7 = wound healing rate at 28 days post‐operative.