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. 2023 Jan 30;2023(1):CD006207. doi: 10.1002/14651858.CD006207.pub6

6. Results from trials of complex interventions compared to control.

Study Comparison (see Table 4 for details of interventions) Reported outcomes Results
Complex hygiene and sanitation interventions compared to control
Chard 2019
cluster‐RCT
Laos
Complex sanitation intervention and education vs none Pupil‐reported symptoms of respiratory infection over 1 week NS difference between groups. 29% of intervention group; 32% control group; adjusted risk ratio 1.08 (95% CI 0.95 to 1.23)
Hartinger 2016
cluster‐RCT
Peru
Cooking and sanitation provision and education vs none Number of ARI episodes per child‐year NS difference between groups. Risk ratio for intervention to control 0.95 (95% CI 0.82 to 1.10)
Huda 2012
cluster‐RCT
Bangladesh
Sanitation provision and education vs none Respiratory illness 12.6% in intervention group; 13.0% in control group. Not adjusted for multiple outcome measurements. No CIs reported.
Najnin 2019
cluster‐RCT
Bangladesh
Sanitation and behaviour change intervention (plus cholera vaccine) vs none Respiratory illness in past 2 days 2.8% in intervention group; 2.9% in control group

ARI: acute respiratory infection
CI: confidence interval
cluster‐RCT: cluster‐randomised controlled trial
NS: non‐significant
RCT: randomised controlled trial
vs: versus