Local thyroid hormone action of peripheral tissues in LPS-induced NTIS. Male THAI mice were treated with 150 μg/animal LPS i.p.; Luciferase expression represents local TH-action. (A–C) YA (2–3 months old), (A) hepatic Luciferase mRNA levels, (B) hepatic Dio1 mRNA levels, (C) small intestine Luciferase mRNA levels, (D–F) AG (1 year old), (D) hepatic luciferase mRNA levels, (E) hepatic Dio1 mRNA levels, (F) small intestine Luciferase mRNA levels. n(YA) = 5/group; n(AG) = 7–9/group; figure shows Tukey Box Plots, α = 0.05; *p < 0.05, **p < 0.01, ***p < 0.001.