Table 2.
Clinicopathological characteristics of ovarian cancer with and without lymph node metastasis
| Negative lymph node n (%) | Positive lymph node | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pelvic | Para-aortic | Pelvic + Para-aortic | ||||||||
| n (%) | OR (95% CI) | p | n (%) | OR (95% CI) | p | n (%) | OR (95% CI) | p | ||
| Total | 8010 (71.0) | 1495(13.3) | NA | NA | 1285(11.4) | NA | NA | 485 (4.3) | NA | NA |
| Age (year) | ||||||||||
| < 50 | 2398 (75.6) | 356 (11.2) | 1 | 283 (8.9) | 1 | 137 (4.3) | 1 | |||
| ≥ 50 | 5612 (69.3) | 1139(14.0) | 0.93(0.77–1.12) | 0.447 | 1002(12.4) | 0.89(0.77–1.04) | 0.149 | 348 (4.3) | 0.68(0.53–0.87) | 0.002 |
| Histology | ||||||||||
| Type I | 3105 (88.2) | 205 (5.8) | 1 | 167 (4.7) | 1 | 45 (1.3) | 1 | |||
| Type II | 4905 (63.3) | 1290(16.6) | 1.32(1.06–1.65) | 0.015 | 1118(14.4) | 1.30(1.05–1.61) | 0.018 | 440 (5.7) | 1.85(1.29–2.65) | 0.001 |
| Tumor Stage | ||||||||||
| Stage T1 | 4158 (95.4) | 88 (2.0) | 1 | 101 (2.3) | 1 | 13 (0.3) | 1 | |||
| Stage T2 | 1401 (81.1) | 143 (8.3) | 4.03(2.99–5.43) | 0.000 | 149 (8.6) | 3.78(2.85–5.01) | 0.000 | 34 (2.0) | 4.68(2.32–9.43) | 0.000 |
| Stage T3 | 2219 (47.6) | 1134(24.3) | 17.16(13.36–22.05) | 0.000 | 916 (19.7) | 11.31(8.92–14.36) | 0.000 | 389 (8.4) | 22.86(12.66–41.28) | 0.000 |
| Stage TXM1 | 194 (40.2) | 127 (26.3) | 23.15(16.30–32.89) | 0.000 | 114 (23.7) | 15.22(10.76–21.53) | 0.000 | 47 (9.8) | 30.39(15.08–61.23) | 0.000 |
| Unknown | 38 (79.2) | 3 (6.2) | 5 (10.4) | 2 (4.2) | ||||||
| Pathology Grade | ||||||||||
| Grade 1 | 1534 (90.9) | 85 (5.1) | 1 | 49 (2.9) | 1 | 19 (1.1) | 1 | |||
| Grade 2 | 2423 (81.0) | 276 (9.2) | 0.86(0.61–1.22) | 0.404 | 212 (7.1) | 1.35(0.91–1.98) | 0.134 | 80 (2.7) | 0.86(0.61–1.22) | 0.404 |
| Grade 3 | 4053 (61.4) | 1134(17.2) | 1.18(0.85–1.64) | 0.316 | 1024 (15.5) | 2.22(1.55–3.20) | 0.000 | 386 (5.9) | 1.18(0.85–1.64) | 0.316 |
| Tumor size | ||||||||||
| ≤ 5 cm | 1285 (71.6) | 235 (13.1) | 1 | 181 (10.1) | 1 | 94 (5.2) | 1 | |||
| 5-10 cm | 1767 (69.2) | 376 (14.7) | 1.02(0.86–1.21) | 0.820 | 284 (11.1) | 0.99(0.83–1.18) | 0.881 | 126 (5.0) | 0.88(0.67–1.17) | 0.391 |
| 10-15 cm | 1643 (74.7) | 229 (10.4) | 0.85(0.71–1.02) | 0.081 | 242 (11.0) | 1.16(0.96–1.40) | 0.132 | 86 (3.9) | 0.86(0.63–1.17) | 0.337 |
| 15-20 cm | 814 (78.7) | 98 (9.5) | 0.82(0.64–1.05) | 0.110 | 99 (9.6) | 1.06(0.83–1.36) | 0.642 | 23 (2.2) | 0.58(0.36–0.93) | 0.023 |
| > 20 cm | 520 (82.8) | 36 (5.7) | 0.61(0.43–0.86) | 0.005 | 61 (9.7) | 1.36(1.00–1.85) | 0.049 | 11 (1.8) | 0.59(0.31–1.13) | 0.113 |
| Unknown | 1981 (64.6) | 521 (17.0) | 418 (13.7) | 145 (4.7) | ||||||