Table 1.

GO and KEGG enrichment analysis of CD276 and their interactors

Ontology	ID	Description	GeneRatio	Genes	pvalue	p.adjust	qvalue
BP	GO:0032729	positive regulation of interferon-gamma production	4/30	HRAS, LGALS9, TNF, CD276	3.43e-06	0.004	0.003
BP	GO:0032649	regulation of interferon-gamma production	4/30	HRAS, LGALS9, TNF, CD276	1.98e-05	0.010	0.007
BP	GO:0032609	interferon-gamma production	4/30	HRAS, LGALS9, TNF, CD276	3.09e-05	0.010	0.007
CC	GO:0005925	focal adhesion	5/33	CD9, ITGB5, TRIOBP, MPRIP, FBLIM1	5.27e-04	0.014	0.012
CC	GO:0005924	cell-substrate adherens junction	5/33	CD9, ITGB5, TRIOBP, MPRIP, FBLIM1	5.45e-04	0.014	0.012
CC	GO:0030055	cell-substrate junction	5/33	CD9, ITGB5, TRIOBP, MPRIP, FBLIM1	5.70e-04	0.014	0.012
MF	GO:0005178	integrin binding	3/31	CD9, ITGB5, LGALS8	0.002	0.091	0.076
MF	GO:0050839	cell adhesion molecule binding	5/31	CD9, ITGB5, LGALS8, TRIM25, MPRIP	0.002	0.091	0.076
KEGG	hsa04510	Focal adhesion	4/14	ELK1, HRAS, ITGA9, ITGB5	3.06e-04	0.018	0.013
KEGG	hsa05205	Proteoglycans in cancer	4/14	ELK1, HRAS, ITGB5, TNF	3.30e-04	0.018	0.013
KEGG	hsa05410	Hypertrophic cardiomyopathy	3/14	ITGA9, ITGB5, TNF	4.46e-04	0.018	0.013