TABLE 4.

Recommendations for vitamin C dosing according to the ESPEN Micronutrient Guideline (47) and nutrition in the ICU guidelines.

Patient group	Examples	Dosage
Parenteral nutrition (47, 130, 131)	Supplementary or total parenteral nutrition	100–200 mg/d (2)
Patients with chronically elevated demands (47)	COPD, CAD, alcoholism, diabetes mellitus, smokers, heart failure, chronic dialysis	200–500 mg/d (2)
Patients in the acute phase of critical illness (47)	I/R Injury: cardiac surgery, stroke, resuscitation, clamping of large vessels, tourniquet Increased losses: extracorporeal circulation, exsudation Systemic inflammation: sepsis, shock, polytrauma	2–3 g/d (47)

CAD, coronary artery disease; COPD, chronic obstructive pulmonary diseases; I/R: ischemia-reperfusion.