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. Author manuscript; available in PMC: 2023 Jan 30.
Published in final edited form as: Brain Behav Immun. 2021 Jul 8;97:135–149. doi: 10.1016/j.bbi.2021.07.005

Fig. 4. Thirteen weeks of moderate voluntary, intermittent running exercise (RE) resulted in microglia with highly ramified processes in the hippocampus.

Fig. 4.

A-F shows representative examples of microglial morphology traced with Neurolucida from the hippocampus of naive (A, D), GWI-SED (B, E), and GWI-RE (C, F) groups. The bar charts G-J compare the various morphometric measures of microglia between naïve, GWI-SED, and GWI-RE groups, which include the average area occupied by individual microglia (G), the total process length (H), the number of nodes (I), and the number of process endings (J). The bar charts K-O compare the number of intersections (K), total process length (L), surface area (M), number of nodes (N), and number of process endings (O) between naïve, GWI-SED, and GWI-RE groups at 0–10 μm, 10–20 μm, 20–30 μm, 30–40 μm, 40–50 μm, and 50 – 60 μm distances from the soma. *, p < 0.05; **, p < 0.01; ***, p < 0.001. Scale bar, A-F = 25 μm.