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. 2023 Jan 26;17:237–260. doi: 10.2147/DDDT.S390883

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© 2023 Huang et al.

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The expression levels of PI3K-AKT pathway molecules and apoptosis-related molecules in mouse myocardial tissues were quantitated. (A–D) The mRNA levels of PI3K (A), AKT (B), Bcl-2 (C), and Bcl-xL (D) in mouse myocardial tissues of the indicated groups were quantitated by qPCR. n=6 for each group; ^##P<0.01, Compared with the CON group; ^▲▲P<0.01, compared with the DCM group; **P<0.01, compared with the ZGJTSXFL group; ^ΔΔP<0.01, compared with the ZGJTSXFH group. (E–I) The protein levels of phosphorylated PI3K (p-PI3K; (F), phosphorylated AKT (p-AKT; (G), Bcl-2 (H), and Bcl-xL (I) in mouse myocardial tissues of the indicated groups were quantitated by Western blot assay. Representative images of Western blot bands are shown (E), and the relative expressions were summarized. n=6 for each group; ^##P<0.01, compared with the CON group; n=6 for each group; ^▲▲P<0.01, ^▲P<0.05, compared with the DCM group.