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. 2022 Aug 19;2(6):495–516. doi: 10.1021/acsmeasuresciau.2c00033

Table 4. Comparison of Relevant Technologies Competing with IPG.

  description advantages limitations sensitivity/specificity for DVT
IPG circumferential electrodes are placed on the limb; high-frequency/low voltage current is passed to measure impedance •requires only slight skin contact •false positive DVT analysis may result from skin/electrode contacts if scar tissue is present 75%/90%109
•can be produced from soft/flexible material
•insensitive to location of measurement •low sensitivity
•ease of use
SGP flexible strain gauge imbibed with mercury is placed around the limb; changes in the blood volume result in changes in the impedance of the strain gauge •relatively inexpensive •sensitive to temperature variations 83%/81%110
•does not require skilled technician •requires use of mercury (toxic)
PPG blood volume is estimated by utilizing light from LEDs and photodetectors •high sensitivity for arterial disease •must fit tightly onto body 94%/73.1%109
•low-cost technology •LED/photodetector consumes high power
•ease of use, widely used •low sensitivity/specificity for venous reflux
APG chamber filled with air is placed around the limb; displacement of air is used to measure changes in blood volume •relative ease of use •low sensitivity for venous reflux 85%/91%109
•more reproducible than SGP
•has replaced SGP and PPG in diagnosis of CVI