Table 1.
Structural and functional cardiac abnormalities | Repolarisation and conduction abnormalities | Haemodynamic abnormalities | Peripheral vascular abnormalities |
---|---|---|---|
Decreased left ventricular mass (LVM) Decreased left ventricular systolic function Mitral valve prolapse Pericardial effusions Myocardial fibrosis |
Sinus node dysfunction: Sinus* bradycardia, Sinus pauses and Junctional escape rhythms AV conduction delay QTc prolongation and increased QT dispersion (secondary to electrolyte deficiency and medications) |
Hypotension* Orthostatic hypotension and tachycardia* Syncope* Autonomic dysfunction |
Acrocyanosis Dysregulation of peripheral vasoconstriction and vasodilation |
→ Increased risk of sudden cardiac death ← |
*Denotes the most common complications