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Chronic A61603 treatment did not change engineered heart tissue (EHT) intrinsic contraction rate. A: intrinsic rate of spontaneous EHT contractions measured before and after chronic (2 wk) treatment with vehicle or A61603 (means ± SE, n = 5–7/group, P values for mixed effects analysis). B: no change in intrinsic rate after treatment relative to before treatment (P value for unpaired t test).
