Table 1.
SAN characteristics of select animal models compared with humans
| Species | SAN Length, mm | SAN Width, mm | Normal HR, Beats/Min (25) | Cycle Length, ms (26) | Sinoatrial Conduction Time, ms (26) | Action Potential Amplitude, mV (26) | Action Potential Duration, ms (26) | Maximum Diastolic Potential, mV (26) | Diastolic Depolarization Rate, mV/s (26) |
|---|---|---|---|---|---|---|---|---|---|
| Human | 8−21.5 (8) | 1−5 (8, 27) | 60−100 | 828 (28) | 82 (29) | 72 | 309 | −62 | 48.9 (28) |
| Mouse | 1.5 (30) | 450−750 | 144 | 4 | 56 | 82 | −51 | 117 | |
| Rabbit | 6−7 (27) | 2 (27) | 180−350 | 386 | 32 | 66 | 180 | −61 | 83 |
| Dog | 5−15 (27, 31) | 2 (27, 31) | 70−120 | 542 (31) | 45 (31) | 56 (32) | 220 (33) | −56 (32) | 72 (34) |
| Cat | 7.4 (27) | 2.2 (27) | 120−140 | 418 | 29 | 60 | 202 | −59 | 71 |
| Guinea pig | 4 (27) | 1 (27) | 200−300 | 275 | 12 | 67 | 137 | −57 | 121 |
Displayed are data values (reference citation). SAN, sinoatrial node; HR, heart rate.