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. 2023 Jan 31;28:100600. doi: 10.1016/j.bbih.2023.100600

Fig. 2.

Fig. 2

The effect of exercise on the TCR-β diversity and MHC class of SARS-CoV-2 specific T-cells. SARS-CoV-2 specific TCR-diversity metrics, (a) total number of productive templates, (b) unique rearrangements, (c) productive frequency, and (d) number of SARS-CoV-2 productive rearrangement templates adjusted for number of T-cells within 1mL of blood (SARS-CoV-2 clones/mL), in response to exercise. (e) The proportion of SARS-CoV-2 clones that recognize each major region and ORF of the virus in response to exercise. (f) The absolute change of SARS-CoV-2 clones mobilized (80%-Rest) and egressed (+1h-80%) with exercise. (g) The proportion and number of SARS-CoV-2 MHC class (MHC I and II) restriction in response to exercise. Data are mean ± SEM. Significance is indicated by * (p < 0.05); ** (p < 0.01). MHC = Major Histocompatibility Complex; ORF = Open Reading Frame.