Table 2.

Outcome data for all patients combined and for group 1 and groups 2–4 separately

	All patients			Group 1 (cancer)			Groups 2–4 (other risk groups)
	All (n = 134)	Control (n = 66)	Plasma (n = 68)	All (n = 56)	Control (n = 28)	Plasma (n = 28)	All (n = 78)	Control (n = 38)	Plasma (n = 40)
Overall improvement rate (95% CI)
At 28 d		0.622 (0.503–0.742)	0.725 (0.615–0.825)		0.458 (0.286–0.673)	0.821 (0.663–0.935)		0.730 (0.582–0.859)	0.656 (0.509–0.798)
At 56 d		0.737 (0.623–0.840)	0.817 (0.716–0.899)		0.667 (0.481–0.841)	0.929 (0.796–0.987)		0.784 (0.642–0.898)	0.735 (0.592–0.861)
At 84 d		0.754 (0.641–0.853)	0.817 (0.716–0.899)		0.667 (0.481–0.841)	0.929 (0.796–0.987)		0.811 (0.672–0.917)	0.735 (0.592–0.861)
Median (95% Cl) time to improvement (d)		18 (11–28)	12.5 (10–17)		31 (15–NA)	13 (7–14)		11 (8–21)	12 (10–28)
Overall survival rate (95% Cl)
At 28 d		0.835 (0.715–0.908)	0.864 (0.754–0.927)		0.710 (0.485–0.850)	0.929 (0.743–0.982)		0.918 (0.767–0.973)	0.815 (0.650–0.908)
At 56 d		0.765 (0.636–0.854)	0.832 (0.717–0.903)		0.710 (0.485–0.850)	0.893 (0.704–0.964)		0.803 (0.631–0.901)	0.787 (0.618–0.888)
At 84 d		0.748 (0.616–0.840)	0.815 (0.696–0.890)		0.665 (0.440–0.817)	0.893 (0.704–0.964)		0.803 (0.631–0.901)	0.753 (0.576–0.864)
Overall need for mechanical ventilation (n = 130)
No ventilation	93 (71.5%)	44 (71.0%)	49 (72.1%)	38 (71.7%)	16 (64.0%)	22 (78.6%)	55 (71.4%)	28 (75.7%)	27 (67.5%)
Mechanical ventilation	37 (28.5%)	18 (29.0%)	19 (27.9%)	15 (28.3%)	9 (36.0%)	6 (21.4%)	22 (28.6%)	9 (24.3%)	13 (32.5%)