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. 2022 Oct 15;270(2):851–863. doi: 10.1007/s00415-022-11402-6

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Longitudinal headache data from medically managed IIH patients with active disease (papilloedema present at enrolment), and LOESS smoothers added to show trends across the categories. a Headache frequency (days per month). b Migraine-like headache frequency (days per month). c Headache mean severity of predominant headache (0–10 numerical rating scale). d Headache Impact Test 6 (HIT6) (quality of life measure score 36–78)