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. 2022 Aug 31;20(10):1941–1955. doi: 10.2174/1570159X20666220222145735

Table 1.

Quality of included studies.

Study NHMRC Evidence Hierarchy 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Total
Safarinejad 2011 [20] Level II Randomised controlled trial Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 16/16 (100%)
Safarinejad 2010 [21] Level II Randomised controlled trial Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 16/16 (100%)
Segraves 2004 [17] Level II Randomised controlled trial Yes Yes Yes Yes Yes Na Yes Yes Na Na Na Yes Na Yes Yes Yes 11/11 (100%)
Thase 2006 [22] Level II Randomised controlled trial Yes Yes Yes Yes Yes Na Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 15/15 (100%)
Clayton 2004 [23] Level II Randomised controlled trial Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes Yes Yes Yes Yes 15/16 (94%)
Kennedy 2006 [24] Level II Randomised controlled trial Yes Yes Yes No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 15/16 (94%)
Hartmann 2012 [25] Level III-3 Interrupted time series without a parallel control group Yes Yes Yes Yes NA NA Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes 14/14 (100%)
DeFronzoDobkin 2006 [26] Level III-3 Interrupted time series without a parallel control group Yes Yes Yes Yes No NA Yes Yes Yes NA Yes Yes Yes Yes Yes Yes 13/14 (93%)
Segraves 2001 [27] Level III-3 Interrupted time series without a parallel control group Yes Yes Yes Yes No NA Yes Yes Yes Yes Yes Yes Yes Yes Na Yes 13/15 (87%)
Mathias 2006 [28] Level III-3 Interrupted time series without a parallel control group Yes Yes Yes No NA NA Yes Yes No No No Yes Yes Yes No Yes 9/14 (64%)
Gitlin 2002 [29] Level IV Case series with either post-test or pre-test/post-test outcomes Yes Yes Yes Yes No NA Yes Yes Yes NA No Yes Yes Yes No Yes 11/14 (79%)