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. 2022 May 16;20(6):1241–1252. doi: 10.2174/1570159X19666210809101248

Table 1.

Demographics of participants, clinical information and ECT parameters for each included study.

Study Participants ECT
ECT Patients Comparisons Diagnosis Age, Years: Mean (s.d.) Female Medication Clinical Assessment (PANSS Total Score) Electrode Placement Mean (s.d.) Number of ECT Interventions
Wolf et al. [34] 8 SZ, 2 scans 10 MDD, 2 scans;
10 HC, 1 scan		 DSM-IV 31.1 (8.4) 3 Yes Pre-ECT: 76.4 (22.0);
Post-ECT: 35.8 (29.3);
Reduction: 87.5%		 RUL 12.4 (1.8)
Wang et al. [35] 21 SZ, 2 scans 21 SZ (no ECT), 2 scans;
23 HC, 1 scan		 SCID-I/P 29.29 (7.1) 11 Yes Pre-ECT: 71.6 (8.4);
Post-ECT: 49.7 (9.6);
Reduction: 52.6%		 BL 11.5 (1.1)
Gong et al. [36] 33 TRS, 1 scan;
20 AE, 1 scan;
4 SA, 1 scan.		 None DSM-IV-TR TRS, 31.5 (10.6);
AE, 27.5 (6.0);
SA, 34.5 (9.7)		 TRS, 9;
AE, 9;
SA, 2		 Yes Pre-ECT: TRS, 94.2 (18.0); AE, 101.1 (22.6); SA, 88.3 (21.9);
Post-ECT: TRS, 51.6 (16.9); AE, 52.8 (14.6); SA, 54.5 (23.2);
Reduction: TRS, 67.4%; AE, 67.5%; SA, 62.8%		 BL 10.5 (2.4)
Xi et al. [37] 57 SZ, 1 scan None DSM-IV-TR RS: 31.0 (10.2);
NRS: 29.7 (8.5)		 20 Yes Pre-ECT: RS, 94.1 (19.2); NRS, 98.7 (21.0);
Post-ECT: RS, 40.0 (7.1); NRS, 63.7 (13.8);
Reduction: RS, 84.7%; NRS, 51.0%		 UL SR, 10.3 (2.0);
NSR, 10.0 (2.9)
Huang et al. [38] 21 SZ, 2 scans 21 SZ (no ECT), 2 scans;
23 HC, 1 scan		 SCID-I/P 29.29 (7.1) 11 Yes Pre-ECT: 71.6 (8.4);
Post-ECT: 49.7 (9.6);
Reduction: 52.6%		 BL 11.5 (1.1)
Li et al. [39] 34 SZ, 29 SZ had 2 scans 34 HC, 1 scan SCID-I/P 29.35 (8.47) 24 Yes Pre-ECT: 82.43 (7.28);
Post-ECT: 55.93 (12.26);
Reduction: 42.4%		 BL 9.1 (1.1)
Sambataro et al. [40] 8 SZ, 2 scans 10 MDD, 2 scans;
10 HC, 1 scan		 DSM-IV 31.1 (8.4) 3 Yes Pre-ECT: 76.4 (22.0);
Post-ECT: 35.8 (29.3);
Reduction: 87.5%		 RUL 12.4 (1.8)
Wang et al. [41] 21 SZ, 2 scans 21 SZ (no ECT), 2 scans;
23 HC, 1 scan		 SCID-I/P 29.29 (7.1) 11 Yes Pre-ECT: 71.6 (8.4);
Post-ECT: 49.7 (9.6);
Reduction: 52.6%		 BL 11.5 (1.1)
Yang et al. [42] 47 SZ, 2 scans none ICD-10 30.23 (9.65) 16 Yes Pre-ECT: 94.62 (18.87);
Post-ECT: 51.62 (16.16);
Reduction: 67.81%, range from 32% to 100%		 BL 9.15 (2.21)
Thomann et al. [43] 9 SZ, 2 scans 12 MDD, 2 scans;
9 HC, 1 scan		 DSM-IV 34.2 (12.3) 3 Yes 4 response;
5 partial response		 RUL 11.3 (1.7)
Jiang et al. [44] 21 SZ, 2 scans 21 SZ (no ECT), 2 scans;
23 HC, 1 scan		 SCID-I/P 29.29 (7.1) 11 Yes Pre-ECT: 71.6 (8.4);
Post-ECT: 49.7 (9.6);
Reduction: 52.6%		 BL 11.5 (1.1)
Jiang et al. [45] 21 SZ, 2 scans 21 SZ (no ECT), 2 scans;
23 HC, 1 scan		 SCID-I/P 29.29 (7.1) 11 Yes Pre-ECT: 71.6 (8.4);
Post-ECT: 49.7 (9.6);
Reduction: 52.6%		 BL 11.5 (1.1)

Abbreviations: TRS: treatment-resistant schizophrenia, AE: schizophrenia patients with an acute episode, SA: schizophrenia patients with suicide attempts, MDD: major depressive disorder, HC: healthy control, RS: Responders, NRS: Non-Responders, BL: bilateral, RUL: right unilateral