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. 2023 Jan 30;13:27. doi: 10.1038/s41398-023-02327-3

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Variance explained for depression B Variance explained for anxiety. LDI Long-term difficulties inventory; LTE List of threatening experiences. The significance of the 55 interaction tests (11 PRS × 5 stress-related exposures) was adjusted for multiple testing using the false discovery rate (FDR < 0.05). For depression, 48 tests were significant (p-value in black), and for anxiety, 24 tests were significant (p-value in black).