Fig. 3. Interaction between PRSs and stress-related exposures for depression and anxiety.
DI Long-term difficulties inventory; LTE List of threatening experiences. The PRS used in the interaction plot was at the most significant p-thresholds. LDI interacted with PRSDep at p-threshold = 0.5 and PRSAnx at p-threshold = 0.1. LTE interacted with PRSDep at p-threshold = 1.0 × 10–05 and PRSAnx at p-threshold = 0.1. Social support interacted with PRSDep at p-threshold = 0.5 and PRSAnx at p-threshold = 0.05. Childhood trauma interacted with PRSDep at p-threshold = 0.5 and PRSAnx at p-threshold = 0.05. Loneliness interacted with PRSDep at p-threshold = 0.001 and PRSAnx at p-threshold = 0.05.