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. 2023 Jan 17;13:1080501. doi: 10.3389/fimmu.2022.1080501

Figure 2.

Figure 2

The distribution of CD163+ and CCR2+ peripheral blood monocytes in patients with colon and rectal cancers. Individual profiles of CCR2+ and CD163+ monocyte subsets for each patient with rectal and colon cancers. (A), The distribution of monocytes of classical (CD14+CD16-), intermediate (CD14+CD16+) and non-classical (CD14-CD16+) populations expressing CCR2 (upper panel) and CD163 (lower panel) is demonstrated before and after NAC and after surgical resection in rectal cancer patients. (B), The distribution of monocytes of classical (CD14+CD16-), intermediate (CD14+CD16+) and non-classical (CD14-CD16+) populations expressing CCR2 (upper panel) and CD163 (lower panel) is demonstrated before and after surgical resection in colon cancer patients. (C), Associations of CCR2-expressing monocyte subsets with hematogenous and lymphatic metastasis in rectal cancer patients. (D), Associations of CD163-expressing monocyte subsets with hematogenous and lymphatic metastasis in colon cancer patients. M0, metastasis-negative status, M1, metastasis-positive status. N0, lymph node-negative status, N1-3, lymph node-positive status.