Table 1.
Monocyte subpopulations` content in healthy individuals and CRC patients.
Subpopulations | Healthy donors (N=42) |
Cancer patients | ||
---|---|---|---|---|
Colorectal cancer (N=70) |
Colon cancer (N=42) |
Rectal cancer (N=28) |
||
CD14+CD16-, % | 82,06 (71,36-85,13) |
83,49 (77,21-88,25) |
84,89 (77,33-88,43) |
82,66 (76,36-86,35) |
CD14+CD16+, % | 2,35 (1,89-4,16) |
2,74 (2,3-7,3) |
2,79 (1,8-4,12) |
2,69 (1,93-4,1) |
CD14-CD16+,% | 5,99 (2,75-8,02) |
4,62 (1,98-7,33) |
3,62 (1,72-7,28) p=0,04 |
5,94 (3,38-7,6) |
CD14+CD16-CD163+,% | 95,27 (85,44-98,73) |
89,79 (73,93-99,2) |
94,44 (73,93-99,37) |
87,53 (77,5-97,36) |
CD14+CD16-CCR2+,% | 61,00 (45,58-79,53) |
70,12 (29,58-91,4) |
68,47 (40,93-80,65) |
85,94 (19,09-95,11) |
CD14+CD16+CD163+,% | 94,51 (86,89-97,87) |
92,81 (81,9-96,45) |
92,8 (83,89-96,45) |
93,13 (80,81-96,18) |
CD14+CD16+CCR2+,% | 18,04 (11,88-41,84) |
18,95 (10,77-48,47) |
23,48 (6,55-51,85) |
10,17 (2,96-18,55) |
CD14-CD16+163+,% | 42,12 (20,43-85,77) |
56,73 (23,51-58,19) |
58,88 (26,88-94,3) |
43,15 (21,14-65,17) |
CD14-CD16+CCR2+,% | 4,39 (0,65-7,17) |
5,85 (0,69-6,83) |
7,25 (0,97-12,43) |
2,96 (0,47-12,69) |
p – difference between colon and rectal cancer groups.