Table 1.

Fertility studies related to the hypothalamus and pituitary gland.

Authors (reference)	Type of study	Study design	Aim	Results	Conclusion
Abbara et al. (19)	in vivo study (human) female	Comparative study	Evaluation of gonadotropin levels in a group of 243 patients with hyperprolactinemia	In patients with PCOS and hyperprolactinemia, there is an increase mainly in LH	Depending on the severity of hyperprolactinemia, a variable pattern of gonadotropin secretion is noted
Feng et al. (20)	in vivo study (human) female	Comparative study	Evaluation of the effectiveness of the use of Bushen-zhu-yun decoction (BSZY-D) and dopamine agonists in infertile patients with hyperprolactinemia	Adding decoction to traditional treatment results in a reduction in the number of miscarriages, fewer side effects, lower prolactin levels	Bushen-zhu-yun decoction (BSZY-D) and dopamine agonists are characterized by synergism of action, which is beneficial
Sermondade et al. (21)	in vivo study (human) male	Meta-analysis	Confirmation of the relationship between BMI and sperm count	Overweight and obesity were associated with an increased prevalence of azoospermia or oligozoospermia	BMI is associated with sperm count