Table 4.

Comparison of management and outcomes between the studied groups

Group	Group 1 Original/Alpha [N = 74]	Group 2 Delta/Omicron [N = 34]	p value
IVIG, n [%]	71 [96]	34 [100]	0.55**
Steroids, n [%]	64 [87]	25 [74]	0.11**
Steroids—total dose (mg/kg), median (IQR)	12.6 (10.5–17.8)	16.4 (13.3–19.5)	0.03*
Pulses of steroids, n [%]	5 [6.8]	2 [5.9]	1.0**
Milrinone, n [%]	23 [31]	7 [21]	0.36**
Dopamine, n [%]	8 [11]	3 [9]	1.0**
Epinephrine, n [%]	6 [8.1]	4 [11.8]	0.72**
Duration of vasoactive support (days), median (IQR)	7 (6–9)	8 (5–12)	0.71*
PICU admission, n [%]	12 [16.2]	6 [17.6]	1.0**
PICU LOS (days), median (IQR)	7 (4–9)	6 (3–8)	0.6*
Intubation, n [%]	1 [1,35]	2 [5,8]	0.45**
LOS (days), median (IQR)	11 (9–14)	10 (8–12)	0.065*

IVIG intravenous immunoglobulin, LOS length of stay, PICU pediatric intensive care unit

*p value for Mann‒Whitney U test; **p value for Fisher’s exact test