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. 2022 May 2;206(2):186–196. doi: 10.1164/rccm.202110-2309OC

Figure 4.

Figure 4.

Uty, Cxcl9, and Cxcl10 are colocalized in macrophages, and Uty expression is inversely related to Cxcl9 and Cxcl10 expression. (A–D) Representative images depicting colocalization of in situ probes labeling Cd68/CD68 (red), Uty/UTY (green), and Cxcl9/CXCL9 (white) in mouse (A) and human lung sections (C). Representative images depicting colocalization of in situ probes labeling Cd68/CD68 (red), Uty/UTY (green), and Cxcl10/CXCL10 (white) in mouse (B) and human lung sections (D). (E) Schematic of bone marrow–derived macrophage (BMDM) in vitro experiments. (F and G) Relative expression of Cxcl9 (F) and Cxcl10 (G), as measured by real-time qPCR in BMDMs isolated from WT and Uty-KO mice. *P < 0.05 and **P < 0.01. Scale bars, 50 μm. KO = knockout; WT = wild type.