Table 2.

GO and pathway enrichment analyses of significant genes in ischemic strokes and inflammatory bowel disease.

Term	Category	Observed gene count	Strength	False discovery rate [FDR]
Cellular response to cytokine stimulus	BP	92	0.48	7.00E−16
Cell surface receptor signaling pathway	BP	150	0.33	3.29E−15
Response to cytokine	BP	94	0.45	4.04E−15
Signaling	BP	254	0.21	8.51E−14
Cellular response to organic substance	BP	147	0.32	9.24E−14
Cell communication	BP	254	0.2	3.93E−13
Cellular response to chemical stimulus	BP	167	0.28	3.93E−13
Cytokine-mediated signaling pathway	BP	67	0.52	4.15E−13
Signal transduction	BP	238	0.21	4.45E−13
Regulation of response to stimulus	BP	211	0.23	4.45E−13
Protein binding	MF	283	0.13	6.44E−06
Protein kinase binding	MF	47	0.38	0.00026
Kinase binding	MF	50	0.35	0.00045
Binding	MF	433	0.06	0.0005
Signaling receptor binding	MF	83	0.24	0.00091
Cytokine receptor binding	MF	25	0.5	0.0012
Enzyme binding	MF	102	0.18	0.014
Transcription factor binding	MF	41	0.31	0.0172
Immune receptor activity	MF	15	0.58	0.0172
Extracellular matrix structural constituent	MF	14	0.59	0.018
Plasma membrane	CC	220	0.14	7.74E−05
Cell periphery	CC	225	0.14	7.74E−05
Integral component of plasma membrane	CC	88	0.26	8.33E−05
Cell surface	CC	54	0.34	0.00012
Intrinsic component of plasma membrane	CC	90	0.25	0.00012
Side of membrane	CC	36	0.35	0.0046
Cell junction	CC	94	0.18	0.016
Platelet alpha granule	CC	12	0.64	0.016
Receptor complex	CC	27	0.37	0.0192
Endoplasmic reticulum lumen	CC	23	0.4	0.0286