Table 1. Growth Inhibition of S. pneumoniae and S. aureus of the Active Extract MA60, MAF, and Compounds 2, 4, and 7.
| MICa [μM; multicomponent mixtures in μg/mL] |
|||||
|---|---|---|---|---|---|
|
S. pneumoniae |
S.
aureus |
||||
| sample code | DSM20566 | D39 | ATCC43000 | ATCC25923 | |
| multicomponent mixtures | MAF | 3.16 | 3.16 | 1.00 | 0.77 |
| MA60 | 3.16 | 3.16 | 1.00 | 1.00 | |
| natural product isolates | 2 | 3.16 | 3.16 | 10.00 | 10.00 |
| 4 | 3.16 | 3.16 | 10.00 | 10.00 | |
| 7 | 2.08 | 1.72 | 3.16 | 3.16 | |
| antibiotics | ampicillin | 0.02 | 0.01 | 15.40 | 1.00 |
| rifampicin | 0.01 | 0.02 | 0.003 | 0.003 | |
a
Bacterial suspensions were grown with or without half-logarithmic dilutions of the test samples (in duplicate) at 37 °C overnight. The results represent the mean minimal inhibitory concentration (MIC) from three assays.