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Diagram depicting the genome organization of SARS-CoV-2. The genome of SARS-CoV-2, with a size of ~30 Kb, encodes 4 structural proteins, 16 non-structural proteins (nsps), and 6 accessory proteins. The structural proteins, including spike glycoprotein (S), nucleocapsid (N), membrane (M), and envelope (E) proteins, are important for virus assembly and infection and are the target for the development of vaccines and therapeutics for COVID-19.
