Table 3.
No | Antibodies Name | Current Status | References |
---|---|---|---|
1 | Bebtelovimab | Remain authorized in the U.S. until further notice by the FDA. | [30,83] |
2 | Tixagevimab with cilgavimab |
Remain authorized with the recommendation of repeat dosing every six months with a dose of 300 mg of tixagevimab and 300 mg of Cilgavimab. |
[84,85] |
3 | Sotrovimab | Since 5 April 2022, no longer authorized in any U.S. region; approved in Australia, the UK, and the EU. |
[86,87,88] |
4 | Bamlanivimab with etesevimab | Pausing all distribution. | [81,89] |
5 | Casirivimab with imdevimab | Currently not authorized in any U.S. region; however, it is recommended to be retained for future SARS-CoV-2 variants that may be susceptible. | [33,88,90] |
6 | Amubarvimab/romlusevimab | Approved in China. | [88] |
7 | Regdanvimab (CT-P59) | Approved in the Republic of Korea and the EU. | [88] |
8 | Ronapreve | Approved in Japan, the UK, the EU, and Australia. | [88] |
9 | F61 | Approved for clinical trials in China. | [91] |
10 | Tocilizumab | Authorized for emergency use in June 2021. | [92,93] |
11 | Sarilumab | Clinical trial phase 3. | [94] |
12 | Adalimumab | Clinical trial phase 3. | [95] |
13 | Canakinumab | Clinical trial phase 3. | [96] |
14 | Ravulizumab | Completed clinical phase 3; recruiting phase 4 trials. | [97,98] |
15 | Lenzilumab | Clinical trial phase 3. | [99] |
Abbreviation: EUA, emergency use authorization; FDA, U.S. Food and Drug Administration; mg, milligram.