. 2022 Dec 21;86(1):166–175. doi: 10.1021/acs.jnatprod.2c00880

Table 3. Cytotoxic Effects of NBD-6AHA-Triterpene Conjugates 1 and 2 on Nontumor Cells.

compound	HPF^a	SI^b	IEC-18^a	SI^b	WRL68^a	SI^b
1	39.7 ± 1.2	17	41.0 ± 0.3	2	37.9 ± 0.2	3
2	14.8 ± 1.5	3	14.7 ± 0.7	2	10.0 ± 0.3	1

The IC₅₀ values (μM) were calculated by considering untreated control cells as 100% viability. Cell viability was analyzed using the MTT assay, as described in the Experimental Section.

SI = selectivity index (IC₅₀ nontumor cells/IC₅₀ cancer cells).