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. 2022 Dec 14;46(2):369–376. doi: 10.2337/dc22-1505

Table 2.

Association of UPF consumption when expressed continuously (150 g/day) and categorically (quartiles) with MetS incidence (n = 8,065)

Models* 150 g/increment Quartile 2 Quartile 3 Quartile 4 P for trend
RR 95% CI RR 95% CI RR 95% CI RR 95% CI
1 1.05 1.03–1.07 0.95 0.86–1.05 1.11 1.01–1.21 1.23 1.12–1.34 <0.0001
2 1.05 1.03–1.06 0.98 0.88–1.08 1.15 1.04–1.26 1.24 1.13–1.36 <0.0001
3 1.05 1.0–31.06 0.98 0.89–1.08 1.15 1.04–1.26 1.24 1.13–1.36 <0.0001
4 1.07 1.05–1.08 1.00 0.91–1.11 1.19 1.08–1.32 1.33 1.20–1.47 <0.0001
5 1.04 1.02–1.06 0.98 0.89–1.08 1.14 1.04–1.25 1.19 1.07–1.32 <0.0001
6a 1.04 1.02–1.06 0.98 0.89–1.08 1.14 1.03–1.25 1.18 1.06–1.32 0.0002
6b 1.04 1.02–1.06 0.98 0.89–1.08 1.14 1.04–1.26 1.20 1.07–1.33 <0.0001
6c 1.04 1.02–1.06 0.98 0.89–1.08 1.13 1.03–1.25 1.19 1.07–1.31 <0.0001
*

Models developed in Poisson regression with robust variance were 1) adjustment models, as follows: model 1: nonadjusted; model 2: model 1 plus age, sex, center, race or color, income, school achievement; model 3: model 2 plus smoking, physical activity, alcohol; model 4: model 3 plus energy intake; and model 5: model 4 plus BMI. 2) Additional models were: model 6a: model 5 plus saturated fat, sugar, fiber; model 6b: model 5 plus minimally processed foods and culinary ingredients; and model 6c: model 5 plus weight gain since baseline.

UPF quartiles: quartile 1, <234 g/day; quartile 2, between 234 g/day and 365 g/day; quartile 3, between 366 g/day and 552 g/day; and quartile 4, >552 g/day of UPF consumption. Results for quartiles 2–4 use the first quartile as the reference.