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The number and magnitude of glycosphingolipids increased in sensitized and exposed females is greater than in males. A and B, Volcano plots displaying significantly altered metabolites in sensitized males and females exposed to ozone relative to vehicle control, respectively. A fold change cutoff of 2 or greater is defined as a high-effect size, and p < .05 is used as a cutoff for statistical significance. p values were calculated by 1-way ANOVA with Tukey’s post hoc analysis.
