Table 1.
Baseline data of the included patients stratified by liver fibrosis status
| Variables | Study cohort n = 326 |
With advanced liver fibrosis n = 80 |
Without advanced liver fibrosis n = 246 | P value |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, year | 66.6 ± 11.3 | 72.3 ± 8.4 | 64.8 ± 11.5 | < 0.001 |
| Male, % | 168 (51.5) | 45 (56.3) | 123 (50.0) | 0.331 |
| Education < 12 years, % | 172 (52.8) | 45 (56.3) | 127 (51.6) | 0.547 |
| Risk factors, % | ||||
| Hypertension | 240 (73.6) | 66 (82.5) | 174 (70.4) | 0.038 |
| Diabetes mellitus | 83 (25.5) | 22 (27.5) | 61 (24.8) | 0.630 |
| Hyperlipidemia | 69 (21.2) | 20 (25.0) | 49 (19.9) | 0.334 |
| Coronary heart disease | 46 (14.1) | 15 (18.8) | 31 (12.6) | 0.170 |
| Current smoking | 137 (42.0) | 39 (48.8) | 98 (39.8) | 0.161 |
| Clinical data | ||||
| Systolic blood pressure, mmHg | 136.1 ± 19.7 | 136.4 ± 25.7 | 136.2 ± 17.4 | 0.891 |
| Diastolic blood pressure, mmHg | 82.0 ± 9.9 | 81.2 ± 9.5 | 82.3 ± 10.0 | 0.910 |
| Body mass index, kg/m2 | 24.3 ± 2.5 | 24.1 ± 2.3 | 24.3 ± 2.6 | 0.431 |
| Baseline NIHSS, score | 5.0 (2.0, 8.0) | 6.0 (4.0, 8.0) | 5.0 (2.0, 8.0) | 0.013 |
| PSD at 3-month, % | 91 (27.9) | 32 (40.0) | 59 (24.0) | 0.006 |
| Stroke subtypes, % | < 0.001 | |||
| arge artery atherosclerosis | 149 (45.7) | 25 (31.3) | 124 (50.4) | |
| Cardioembolism | 63 (19.3) | 23 (28.8) | 40 (16.3) | |
| Small vessel occlusion | 91 (27.9) | 19 (23.8) | 72 (29.3) | |
| Others | 23 (7.1) | 13 (16.3) | 10 (4.1) | |
| Side of infarction, % | ||||
| Left | 165 (50.6) | 43 (53.8) | 122 (49.6) | 0.518 |
| Right | 181 (55.5) | 39 (48.8) | 142 (57.7) | 0.161 |
| Laboratory data | ||||
| Platelet, 109/L | 183.8 ± 58.2 | 145.9 ± 39.0 | 196.1 ± 58.2 | < 0.001 |
| Aspartate transaminase, U/L | 29.2 ± 19.2 | 41.0 ± 30.6 | 25.3 ± 11.3 | < 0.001 |
| Alanine transaminase, U/L | 32.6 ± 20.4 | 34.4 ± 29.2 | 32.0 ± 16.5 | 0.363 |
| Total cholesterol, mmol/L | 4.0 ± 1.1 | 4.1 ± 1.0 | 4.0 ± 1.1 | 0.646 |
| Triglyceride, mmol/L | 1.3 (1.0, 1.8) | 1.3 (1.0, 1.8) | 1.3 (1.1, 1.8) | 0.698 |
| High-density lipoprotein, mmol/L | 1.0 ± 0.2 | 1.0 ± 0.3 | 1.0 ± 0.2 | 0.830 |
| Low-density lipoprotein, mmol/L | 2.4 (1.8, 2.9) | 2.4 (1.9, 3.0) | 2.4 (1.7, 2.9) | 0.374 |
| Blood glucose, mmol/L | 5.4 ± 1.6 | 5.3 ± 1.2 | 5.4 ± 1.8 | 0.465 |
| Hs-CRP, mg/L | 4.0 (1.0, 7.1) | 4.0 (1.0, 7.0) | 4.0 (1.4, 7.0) | 0.751 |
Hs-CRP Hypersensitive C-reactive protein, NIHSS National Institutes of Health Stroke Scale, PSD post-stroke depression