TABLE 1.
Summary of genotypic differences between the 67:20 and 67:21 subclones recovered from a 90-year-old patient with gastric ulcer
| Gene no.a | Gene nameb | Gene description | Annotation | Presence in isolatec:
|
|
|---|---|---|---|---|---|
| 67:20 | 67:21 | ||||
| HP0157 | aroK | Shikimic acid kinase I | General | − | + |
| HP0934 | NA | Conserved hypothetical protein | Hypothetical general | − | + |
| HP0315 | vapD | Virulence-associated protein D | Adaptations and atypical conditions | − | + |
| HP0520 to HP0547 | Cag PAI | Cag PAI proteins | Cag PAI | − | + |
| HP0857 | gmhA | Phosphoheptose isomerase | Cell envelope, biosynthesis of surface polysaccharides and lipopolysaccharides | − | + |
| HP1352 | HINFIM | Adenine-specific methyltransferase, type II | Restriction modification | − | + |
| HP0882, HP0085, JHP0165, JHP0956, HP0425 | Unknown | − | + | ||
| HP0491 | rpL28, rpmB | Ribosomal protein L28 | General | + | − |
| HP0962 | acpP | Acyl carrier protein | General | + | − |
| HP1192 | NA | Secreted protein involved in flagellar motility | General | + | − |
| JHP0726 | hsdS_4 | Putative type I restriction modification system, specificity subunit | Restriction modification | + | − |
| HP1382 | NA | Putative endonuclease | Restriction modification | + | − |
| HP1404 | hsdS | Type I restriction modification system | Restriction modification | + | − |
| HP0062, HP0338, JHP0959, HP0436, HP0450, HP0673, HP0681, HP0712, HP0849, HP0984, JHP0950, HP0999, HP1074, JHP0332, HP1250, HP1324, HP1396, HP1397, HP1405, HP1412, HP1439, JHP1408, HP1586 | Unknown | + | − | ||
a
HP numbers correspond to the numbers used by The Institute for Genomic Research for strain 26695, and JHP numbers correspond to those assigned by AstraZeneca for strain J99. For genes present in both strains, only the HP number is given.
b
Gene names and descriptions are according to those provided by The Institute for Genomic Research and Salama et al. (35). NA, not available.
c
+, gene was present; −, gene was undetectable.