Table 4.

Physiologic and ICU resuscitation data by PVD (mm/mm²)

	PVD ≥ 18 t0	PVD < 18 t0	PVD ≥ 18 t6	PVD < 18 t6
Clinical and macrocirculatory data
Temperature, °C	36.1 ± 0.8	36.6 ± 0.5	37.2 ± 11.6	37.6 ± 0.7
Heart rate, bpm	82 ± 15	84 ± 12	89 ± 13	83 ± 13
Mean arterial pressure, mm Hg	77 ± 10	73 ± 9	76 ± 11	77 ± 11
Central venous pressure, mm Hg	10 ± 4	12 ± 5	7 ± 4	9 ± 5
Cardiac index, L/min·m2	2.4 ± 0.8	2.2 ± 0.5	2.7 ± 0.6	2.5 ± 0.7
SVRi, dyn·s·cm−5·m2	2,508 ± 956	2,283 ± 594	2,118 ± 510	2,337 ± 562
Laboratory data
Hemoglobin, g/dL	12.4 ± 1.6	12.6 ± 1.8	12.1 ± 1.3	12.0 ± 2.3
Hematocrit, %	39 [35–41]	40 [34–42]	37 [33–39]	38 [29–40]
pH	7.31 [7.28–7.36]	7.32 [7.29–7.36]	7.36 [7.31–7.38]	7.37 [7.33–7.41]
PaO2, mm Hg	151 [101–265]	160 [107–245]	111 [83–143]	104 [92–117]
PCO2, mm Hg	42 [39–45]	48 [45–60]†	40 [36–45]	36 [33–42]
Mixed venous O2 saturation, %	73 [67–76]	75 [62–79]	67 [64–72]	64 [59–69]
Glucose, g/dL	154 ± 34	168 ± 24	155 ± 34	147 ± 31
Volume resuscitation (first 6 h)
Intravenous crystalloid, L	—	—	1.3 [0.8–2.0]	1.8 [1.1–2.3]
RBC transfusion, n patients; units	—	—	3; 1 [1–3]	3; 2 [2–3]
FFP transfusion, n patients; units	—	—	4; 2 [1–2]	2; 3 [2–4]
Platelet transfusion, n patients; units	—	—	1; 2 [2–2]	2; [2–2]
Urine output, mL	—	—	610 ± 330	590 ± 290
Blood loss, mL	—	—	200 [120–310]	290 [140–390]
6-h volume balance	—	—	(+) 700 ± 830	(+) 1,200 ± 890
Vasopressor support
Phenylephrine, n patients (%); mcg/kg/min	11 (30) 0.6 [0.3–1.0	2 (15) 0.5 [0.5–0.5]	14 (38) 0.6 [0.5–1.1]	4 (31) 0.9 [0.8–0.9]
Inotropic support
Epinephrine, n patients (%) mcg/kg/min	29 (78) 0.03 [0.02–0.05]	9 (69) 0.06 [0.02–0.07]	26 (70) 0.02 [0.01–0.04]	9 (69) 0.03 [0.01–0.09]

Data presented as mean ± standard deviation, median [quartile range], and frequency (%).

^†P < 0.01.

PVD indicates perfused vessel density; T0, ICU admission; T6, 6 hours after ICU admission.