| The cause of infertility should dictate the specific technique (IUI/IVF/ICSI) used for MAR in couples where one or both partners test positive for HBV (Nie et al., 2019). | Strong |
|---|---|
| ⊕○○○ | |
| Women infected with HBV should be informed that MAR does not eliminate the risk of vertical transmission. | GPP |
| HBV can be detected in sperm cells, oocytes, granulosa cells and embryos. This equates with a theoretical risk of vertical HBV transmission that remains to be proven. | Conclusion |
| Existing evidence cannot clarify if the presence of HBV-infection in the male impacts the outcomes of MAR. Multiple studies showed no differences in reproductive outcomes following MAR when comparing seronegative with HBV-seropositive women. | Conclusion |
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