The cause of infertility should dictate the specific technique (IUI/IVF/ICSI) used for MAR in couples where one or both partners test positive for HCV (Garrido et al., 2004; Nesrine and Saleh, 2012; Savasi et al., 2013). | Strong |
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Women testing positive for HCV should be informed that MAR does not eliminate the risk of vertical transmission. | GPP |
The possibility of HCV RNA presence in oocytes cannot be excluded. However, the risk of Hepatitis C transmission through the use of reproductive material remains to be proven. | Conclusion |
There are contradictory results evaluating effects of male HCV-infection on infertility treatments outcomes. Although the fertilization rate has been reported significantly lower in couples with HCV-RNA-positive men, other studies report that HCV-infection does not affect the IVF-ICSI cycle outcomes in these couples. | Conclusion |
There are contradictory results evaluating effects of female HCV infection on infertility treatments outcomes. Although some studies report significantly reduced implantation rates, higher cycle cancelations, and higher FSH use in HCV positive women, other report no significant differences. | Conclusion |