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. 2023 Jan 31;37(3):650–658. doi: 10.1038/s41375-023-01824-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A FDG-PET at baseline shows multiple focal lesions at the axial and appendicular skeleton (yellow arrows). B Follow-up assessment at 3-month after CAR T infusion shows full resolution of focal lesions, but residual FDG uptake located to the lung (red arrow). Matched-simultaneous CXCR4-targeted Pentixafor and DOTATOC PET did not show focal uptake. C Matched-simultaneous FDG and CXCR4 PET 6 months after CAR T depicted new focal lesions at the pelvis and lower limbs in line with relapse (white arrows).