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. 2023 Jan 27;15:29–40. doi: 10.2147/JEP.S398487

Table 2.

Effect of Solvent Fractions of V. auriculifera in Acetic Acid-Induced Writhing Test

Group No of Writhing ±SEM % Analgesic Activity
TW 61.66 ± 1.42
AQF100 mg/kg 40.83 ± 1.30a 33.78
AQF200 mg/kg 34.66 ± 0.98a 43.78
AQF400 mg/kg 30.16 ± 1.07a 51.08
EAF100 mg/kg 44.33 ± 0.42a 28.1
EAF200 mg/kg 37.33 ± 1.28a 39.45
EAF400 mg/kg 34.50 ± 1.56a 44.04
MEF100 mg/kg 37.16 ± 1.42ac 39.73
MEF200 mg/kg 32.50 ± 0.92a 47.29
MEF400 mg/kg 27.00 ± 0.93ad 56.21
ASA 24.16 ± 1.04abdef 60.81

Notes: aAgainst negative control, bagainst AQF 400 mg/kg, cagainst EAF 100 mg/kg, dagainst EAF 400 mg/kg, eagainst MEF 100 mg/kg, fagainst MEF 200 mg/kg; TW, 2% Tween 80 10mL/kg; ASA, Acetylsalicylic acid 150mg/kg; p < 0.05.

Abbreviations: AQF, aqueous fraction; EAF, ethyl acetate fraction; MEF, methanol fraction.