Table 3.
Analgesic Effect of 80% Methanolic Leaf Extracts of V. auriculifera in Hot Plate Test
| Mean Latency Time (sec) ± S.E.M (Percentage of Elongation) | |||||
|---|---|---|---|---|---|
| Group | 0 min | 30 min | 60 min | 90 min | 120 min |
| TW | 3.34 ± 0.12 | 3.64 ± 0.14 | 3.55 ± 0.07 | 3.42 ± 0.04 | 3.19 ± 0.05 |
| ME 100mg/kg | 3.39 ± 0.09 | 5.50 ± 0.46a (33.81) | 4.98 ± 0.03a (28.71) | 4.73 ± 0.03a (27.69) | 4.64 ± 0.12a (31.25) |
| ME 200mg/kg | 3.65 ± 0.25 | 6.41 ± 0.33a (43.21) | 6.26 ± 0.09ab (43.29) | 5.37 ± 0.17ab (36.31) | 5.18 ± 0.10ab (38.41) |
| ME 400mg/kg | 3.71 ± 0.11 | 8.01 ± 0.15abc (54.55) | 7.30 ± 0.18abc (51.36) | 6.61 ± 0.09abc (48.26) | 5.98 ± 0.08abc (46.65) |
| MOR | 3.64 ± 0.17 | 14.16 ± 0.25abcd (72.25) | 13.04 ± 0.22abcd (72.77) | 12.01 ± 0.05abcd (71.52) | 9.89 ± 0.16abcd (67.74) |
Notes: aAgainst TW, bagainst ME 100mg/kg, cagainst ME 200mg/kg, dagainst ME 400mg/kg; TW, 2% Tween 80 10mL/kg; ME, 80% methanol extract; MOR, morphine 10mg/kg; p < 0.05.